Folstein Mini Mental Status Exam templates

File Name
Fig 1.

Graph of the mean memory recall scores from the Hopkins Verbal Learning Test (HVLT) and the score on the Mini-Mental State Examination (MMSE) before and after each course of therapy. x-axis (time points): first number, the course of treatment (1, 2, or 3); second number, the pretreatment assessment (1) or posttreatment assessment (2). Reprinted with permission.

Conversely, treatment can conceivably delay the time to expected cognitive decline in brain tumor patients. This was found in a large phase III randomized trial of motexafin gadolinium (MGd), which was used as a radiation sensitizer in patients with brain metastases. The addition of MGd to whole-brain radiation seemed to improve memory and executive function, and to prolong time to neurocognitive progression in patients with brain metastases from lung cancer. This study incorporated a brief cognitive test battery that took an average of 23 minutes to administer. A screening tool such as the MMSE would not have been able to detect such changes, which are of great significance to the patients and also to pharmaceutical companies that want to demonstrate benefit of a drug to attain US Food and Drug Administration approval. Thus, the risks versus benefits of various treatments on cognitive function, especially those that do not significantly alter survival or time to progression, cannot be determined with the MMSE.

Formal, objective, and standardized neurocognitive testing is a sensitive measure of brain functioning. Furthermore, it has been demonstrated that the combination of clinical prognostic variables and brain function assessments seem to predict survival better than the prognostic variables alone in primary brain tumor patients, and in patients with leptomeningeal or parenchymal brain metastases. Again, a screening tool such as the MMSE has not been demonstrated to predict survival in cancer populations.

The MMSE also does not measure cognitive functions that are likely to be affected by radiation therapy. It contains items that briefly assess aphasia, apraxia, orientation, and attention. However, the cognitive functions affected by radiation are related to frontal-subcortical white matter dysfunction and include impairments of learning and memory, processing speed, executive function, and fine motor control. It cannot be expected that these impairments will be detected by the MMSE.

You might also like

What Is Physical Health? - Definition, Components & Examples
What Is Physical Health? - Definition, Components & Examples
"Nature vs. Nurture: the Example of Psychosis" by Matthew
"Nature vs. Nurture: the Example of Psychosis" by Matthew ...
Mental Status Exam Training, part 2. Thought Process
Mental Status Exam Training, part 2. Thought Process
"Mental" - Sample Clip 01: Paranoid Schizophrenia
"Mental" - Sample Clip 01: Paranoid Schizophrenia

Q&A

avatar
What is and example of mental helath?

(The psychological state of someone who is functioning at a satisfactory level of emotional and behavioral adjustment) as per the dictionary. Simply put it is someone who can cope with most situations they come across. They are usually well adjusted, easy to get along with, educated to an acceptable level of intelligence and shows a mind capable of giving out useful wisdom. Friendly and has a well adjusted listening ear, are quick of whit and are sought after where advice is concerned.

Copyright © . All Rights Reserved