Composition of human brain

La creazione di Adamo

Gray matter, white matter, and myelin were isolated from the frontal lobes of humans aged 10 months, 6 yr, 9 yr, and 55 yr and the lipid compositions of each were determined. Myelin had a much higher lipid content (78–81% of the dry weight) than white matter (49–66%) or gray matter (36–40%). Myelin contained much higher molar percentages of cerebroside and cerebroside sulfate, slightly higher molar percentages of cholesterol, and lower molar percentages of ethanolamine glycerophosphatides and choline glycerophosphatides than gray matter. The molar percentages of serine glycerophosphatides and sphingomyelin were about the same in each tissue.

The aldehyde content of glycerophosphatides, expressed as molar percentage of the total lipoidal residues in each lipid, were as follows: ethanolamine glycerophosphatides from myelin 40–50%; ethanolamine glycerophosphatides from gray matter 21–27%; serine glycerophosphatides from myelin 21–36%; serine glycerophosphatides from gray matter 0.3–3.8%. Choline glycerophosphatides from either tissue contained only traces of aldehydes.

The extra-myelin portion of white matter had a lipid composition that was very similar to that of myelin, but quite different from that of gray matter.

Assuming a molecular weight of 28, 000 for myelin protein(s), it was calculated that for each protein molecule in human myelin there are 186 lipid molecules, 111 of which are polar lipids and 75 of which consist of cholesterol. The over-all molar ratios of the polar lipids are phosphatidal ethanolamine:serine glycerophosphatides:choline glycerophosphatides:sphingomyelin:cerebroside:cerebroside sulfate:ceramide:uncharacterized lipids 25:9:20:9:29:7:3:9. It was calculated that the molar ratio of protein amino acids to polar lipids in human myelin is 2.38 to 1.

Footnotes

  • * Brain Lipids III. For previous papers in this series see J. S. O'Brien, D. L. Fillerup, and J. F. Mead, J. Lipid Res. 5: 109, 1964 and 5: 329, 1964.
  • Received April 1, 1965.
  • Accepted June 25, 1965.

You might also like

Lion Face Painting Make-up Tutorial
Lion Face Painting Make-up Tutorial
The Scarecrow from Wizard of Oz Make Up Face Painting
The Scarecrow from Wizard of Oz Make Up Face Painting
The Brain Unlocked How To Use Your Brain To Create
The Brain Unlocked How To Use Your Brain To Create ...
The human chameleon: Meet the amateur make-up artist who
The human chameleon: Meet the amateur make-up artist who ...
Classification of Brain Tumours / Die Klassifikation der Hirntumoren: Report of the International Symposium at Cologne 30th August - 1st September 1961 ... 1961 (Acta Neurochirurgica Supplement)
eBooks (Springer)
TATEELY Geometric Shape Wooden Building Blocks Intelligence Box Learning Match Classification Blocks Children Learning Toys for Kids Birthday Christmas Gift
Toy (TATEELY)
  • Material: Rubber wood+ Birch plywood,Size:17.8cm*15cm/7 *5.9 .
  • Help to develop kid s intelligence,greatly help to develop children s intelligence and trains users brain and hands.
  • Perfect gifts and great early-education toys for your kids daily entertainment.
  • Helps build early shape, color and size differentiation skills.
  • Improve parent-child communication and emotion / mom and dad can lead and begin the early education during entertaining with your kids.
SPHINX SECOND BRAIN: classification system for freelancers, small businesses, editors, engineers, managers, individuals - information management, PC organization, data security
eBooks (Cooperation TERRA UNIKA / INTELLOG / SOFTEX)
Pracy Pracy Xmas Trees Decorated H.G. Wells Crude Classifications False Curse Life Organized Life Large Christmas Tree Snowflake Ornaments
Home (Pracy)
  • Made Of Metal.
  • An Ideal Choice To Capture Wonderful Family Memories
  • 3 In Diameter
  • With A Silver Hanging Thread
  • Hang From The Christmas Tree, From The Window Or From The Ceiling And Doorways.
Webrich Software IQ Test Lite
Mobile Application (Webrich Software)
  • Over 930 multiple-choice questions.
  • Choose number of questions you would like in each test.
  • Track your progress with beautiful Pie chart.
  • A new module, Progress Meter keeps track of how you are performing in a particular topic
  • Support for both orientations
  • Special algorithm that randomizes questions every time you take a test.

Copyright © . All Rights Reserved